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- W2359195796 abstract "Aim To explore the effect of MHC I matched allogenic renal tumor cells inducing tumor specific cytotoxic T lymphocytes (CTLs). Methods HLA type was defined by HLA serologically test. CTLs were induced by using irradiated known HLA A allogenic renal tumor cells in the presence of IL 2. Phenotypes of the induced CTLs were analyzed by flow cytometer. The MTT test was used to determine cytotoxic activity of the CTLs. Results CTLs induced by allogenic renal tumor cells from 11 patients were showed to be mainly CD8+ and TCR αβ+cells and to have specific cytotoxic activity to the MHC I matched renal cancer cells. Conclusions Renal cancer specific CTLs may be obtained from PBMC by stimulation with MHC I matched allogenic renal tumor cells and were showed to have obviously high cytotoxic activity." @default.
- W2359195796 created "2016-06-24" @default.
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- W2359195796 date "2001-01-01" @default.
- W2359195796 modified "2023-09-28" @default.
- W2359195796 title "Induction of tumor specific cytotoxic T lymphocytes from human peripheral blood by stimulation with MHC I matched allogenic renal cell carcinoma" @default.
- W2359195796 hasPublicationYear "2001" @default.
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