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- W2359200828 abstract "Objective To explore the protective effect of the polysaccharides of tricholoma matsutake(PTM) on hematopoietic function of X-rays irradiated mice.Methods Fifty ICR mice were divided into five groups randomly,10 each group.The mice in normal control group(NC) and radiation control group(IC) were gaster-poured by 0.9% sodium chloride solution.The mice in PTM groups were gaster-poured by three different doses PTM(400,800,1200 mg·kg-1) for 7 d.The mice all groups except NC group were irradiated once with 2.0 Gy X-rays on the eighth day.The conony forming units-spleen(CFU-S),fibrolast colony forming unit(CFU-F),cell cycle of bone marrow cells and micronucleus rate of bone marrow polychromalic erythrocytes(PCE) were detected after radiation for 24 h.Results Compared with IC group,the number of CFU-S in PTM groups decreased significantly(P0.05 or P0.01)and the number of CFU-F increased markedly(P0.05 or P0.01);in high and moderate doses PTM the micronucleus rates of bone marrow PCE and the percentage of bone marrow cells at G1 phase decreased signficantly(P0.05 or P0.01);the percentage of cells at S phase increased signficantly(P0.05 or P0.01).Conclusion PTM has an obvious protective effect on hematopoietic function of X-rays irradiated mice." @default.
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- W2359200828 date "2008-01-01" @default.
- W2359200828 modified "2023-09-23" @default.
- W2359200828 title "Protective effect of polysaccharides of tricholoma matsutake on hematopoietic function of X-rays irradiated mice" @default.
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