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- W2359202499 abstract "Objective: To investigate ultrastructural pathological change of photoreceptors in early diabetic retinopathy (DR) in rats,and to furnish the morphological evidence of visual dysfunction in DR. Methods; The SD rats were chosen and divided at random into normal group (CON) .diabetic groups 1 month (DM1) ,3 month (DM3) and 6 month (DM6) respectively (n = 12). Diabetic rat was induced by injected streptozotocin (60 rug/kg) into abdominal cavity. The blood sugar was tested the foundus was examined once a month before put to death. Then the retina were prepared into the ul-trathin sections and were observed by transmission electron microscope. Results; With blood sugar rising the condition of illnese worsened, the membrane disc of outer segment of visual cell had pathological change from indistinct to enlarged, the interspace of disc were enlarged,and arranged in confusion and crisscross,even broken locally, broken and festered in the middle. The capillaries were from dilated to narrowed. Conclusion;The ultrastructure pathological change of photoreceptor in retina and visual dysfunction are caused by the ischemia and hypoxia." @default.
- W2359202499 created "2016-06-24" @default.
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- W2359202499 date "2002-01-01" @default.
- W2359202499 modified "2023-09-25" @default.
- W2359202499 title "Study on ultrastructural pathological change of visual cell in diabetic rats and its clinical significance" @default.
- W2359202499 hasPublicationYear "2002" @default.
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