Matches in SemOpenAlex for { <https://semopenalex.org/work/W2359242783> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2359242783 abstract "OBJECTIVE:To observe the clinical efficacy and quality of life of thalidomide combined with oxaliplatin,leucovorin,fluorouracil and hydroxycamptothecin for advanced gastric cancer.METHODS:In a randomized manner,41 patients with advanced gastric cancer were divided into a combined treatment group and chemotherapy group.Combined treatment group:thalidomide 100 mg/d,or,first week,and increased by 100 mg every week until 300 mg/d if side effect was tolerance,if not keep 100 mg/d for more than 2 months;L-OHP 85 mg/m2,iv drip 2 h,d1;CF 200 mg/m2,iv drip 2 h,d1-d2;5-FU 400 mg/m2,iv,and then 600 mg/m2,iv drip 22 h,d1-d2;HCPT 5 mg,iv drip 5 h,d1-d5.Chemotherapy group:the same as combined group without thalidomide.The clinical efficacy and quality of life were compared between two groups.RESULTS:The overall response rates in the combined treatment group and chemotherapy group were 50.0%(11/22) and 42.1%(8/19),respectively.The overall response to the combined treatment group was higher than that of the chemotherapy group,but there were no statistically significant difference between two groups(P0.05).The clinically profited rates were 77.3%(17/22) and 52.6%(10/19),respectively.There was a statistically significant difference between two groups(P0.05).The improvement rates of Karnofsky score were 68.2%(15/22) and 36.8%(7/19),respectively.There was a statistically significant difference between two groups(P0.05).Nausea and vomiting were more pronounced in the chemotherapy group(P0.05).Other toxicities were similar.CONCLUSION:Compared with the chemotherapy regimen,thalidomide combined with chemotherapy regimen obviously increase the clinically profiting rate and improve the life quality of patients with advanced gastric cancer." @default.
- W2359242783 created "2016-06-24" @default.
- W2359242783 creator A5029815331 @default.
- W2359242783 date "2010-01-01" @default.
- W2359242783 modified "2023-09-23" @default.
- W2359242783 title "Treatment of advanced gastric cancer with regimen of thalidomide,oxaliplatin, leucovorin,fluorouracil and hydroxycamptothecin" @default.
- W2359242783 hasPublicationYear "2010" @default.
- W2359242783 type Work @default.
- W2359242783 sameAs 2359242783 @default.
- W2359242783 citedByCount "0" @default.
- W2359242783 crossrefType "journal-article" @default.
- W2359242783 hasAuthorship W2359242783A5029815331 @default.
- W2359242783 hasConcept C121608353 @default.
- W2359242783 hasConcept C126322002 @default.
- W2359242783 hasConcept C2776364478 @default.
- W2359242783 hasConcept C2776694085 @default.
- W2359242783 hasConcept C2779609412 @default.
- W2359242783 hasConcept C2780456651 @default.
- W2359242783 hasConcept C2780580376 @default.
- W2359242783 hasConcept C2780852908 @default.
- W2359242783 hasConcept C2780962732 @default.
- W2359242783 hasConcept C2781413609 @default.
- W2359242783 hasConcept C526805850 @default.
- W2359242783 hasConcept C71924100 @default.
- W2359242783 hasConcept C90924648 @default.
- W2359242783 hasConceptScore W2359242783C121608353 @default.
- W2359242783 hasConceptScore W2359242783C126322002 @default.
- W2359242783 hasConceptScore W2359242783C2776364478 @default.
- W2359242783 hasConceptScore W2359242783C2776694085 @default.
- W2359242783 hasConceptScore W2359242783C2779609412 @default.
- W2359242783 hasConceptScore W2359242783C2780456651 @default.
- W2359242783 hasConceptScore W2359242783C2780580376 @default.
- W2359242783 hasConceptScore W2359242783C2780852908 @default.
- W2359242783 hasConceptScore W2359242783C2780962732 @default.
- W2359242783 hasConceptScore W2359242783C2781413609 @default.
- W2359242783 hasConceptScore W2359242783C526805850 @default.
- W2359242783 hasConceptScore W2359242783C71924100 @default.
- W2359242783 hasConceptScore W2359242783C90924648 @default.
- W2359242783 hasLocation W23592427831 @default.
- W2359242783 hasOpenAccess W2359242783 @default.
- W2359242783 hasPrimaryLocation W23592427831 @default.
- W2359242783 hasRelatedWork W2354263381 @default.
- W2359242783 hasRelatedWork W2355660949 @default.
- W2359242783 hasRelatedWork W2359111711 @default.
- W2359242783 hasRelatedWork W2359185126 @default.
- W2359242783 hasRelatedWork W2363692413 @default.
- W2359242783 hasRelatedWork W2364710415 @default.
- W2359242783 hasRelatedWork W2368279076 @default.
- W2359242783 hasRelatedWork W2369493354 @default.
- W2359242783 hasRelatedWork W2370193683 @default.
- W2359242783 hasRelatedWork W2375397633 @default.
- W2359242783 hasRelatedWork W2380929142 @default.
- W2359242783 hasRelatedWork W2383566251 @default.
- W2359242783 hasRelatedWork W2385131479 @default.
- W2359242783 hasRelatedWork W2387075671 @default.
- W2359242783 hasRelatedWork W2389253074 @default.
- W2359242783 hasRelatedWork W2391076936 @default.
- W2359242783 hasRelatedWork W2394318247 @default.
- W2359242783 hasRelatedWork W3030162103 @default.
- W2359242783 hasRelatedWork W3032607892 @default.
- W2359242783 hasRelatedWork W793839062 @default.
- W2359242783 isParatext "false" @default.
- W2359242783 isRetracted "false" @default.
- W2359242783 magId "2359242783" @default.
- W2359242783 workType "article" @default.