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- W2359256880 abstract "Objective To investigate the expression of TPX2,Cirpto-1,MMP-14 in the cancer tissue of the elderly patients with endometrial adenocarcinoma,and to explore the clinical significance of TPX2,Cirpto-1,MMP-14 in the cancer tissue and the correlation with the histopathologic features of thyroid carcinoma. Methods 120 cases of endometrial adenocarcinoma during February 2010 to October 2014 were selected in this study as a research group,and 110 cases of uterine prolapse or uterine fibroids confirmed by the relevant histopathologic examination were selected as the control group. Pathological tissue slice and clinical data were analyzed,and the expression of TPX2,Cirpto-1,MMP-14 were determined by immunohistochemical method. Results Positive expression rate of TPX2,Cirpto-1,MMP-14 in research group was higher than that in control group( P 0. 05). Positive expression rate of TPX2,Cirpto-1,MMP-14 was associated with tumor infiltration depth,lymph node metastasis,tumor size,tumor emboli and largest Ki-67 index. Cirpto-1 had a correlation with TPX2 and MMP-14( r = 0. 58,P = 0. 013; r = 0. 56,P = 0. 014),and TPX2 had a correlation with MMP-14( r = 0. 47,P = 0. 021). Conclusions TPX2,Cirpto-1,MMP-14 are highly expressed in cancer tissue of the elderly patients with endometrial adenocarcinoma. Therefore,it is important to detect TPX2,Cirpto-1,MMP-14 expression levels in the elderly patients with endometrial adenocarcinoma." @default.
- W2359256880 created "2016-06-24" @default.
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- W2359256880 date "2015-01-01" @default.
- W2359256880 modified "2023-09-23" @default.
- W2359256880 title "Expression of TPX2,Cirpto-1,MMP-14 in the tissue of elderly endometrial adenocarcinoma" @default.
- W2359256880 hasPublicationYear "2015" @default.
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