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- W2359302480 abstract "To study the effect of Livial on ER and LDLR of atherosclerotic rabbits.Methord:Rabbits oophorectomized and fed with normal feedstaff were used as control group.An atherosclerosis animal model was created with high cholesterol feed.We studied the effect of livial on the expression of estrogen receptor and low-density lipoprotein receptor mRNA in heart and liver with half quantity RT-PCR.Results:The two receptors expressed in heart and liver;the ER mRNA expression in the heart and liver of control were 0.43±0.12,0.39±0.20,the low-density lipoprotein receptor mRNA expression in the heart and liver were 0.27±0.05,0.86±0.12;The estrogen receptor and low-density lipoprotein receptor mRNA expression in the heart and liver of model separately were 0.29±0.03,0.27±0.06 and 0.04±0.01,0.17±0.02.The mRNA expession of the two receptors reduced than that of the control group.In the livial group,the expession of ER in the heart and liver were 0.41±0.09,0.36±0.06 and significantly increased as compared with the model group(P0.001).The expession of LDLR in the heart and liver were 0.04±0.02,0.18±0.04.Conclusion:The reduce of the two receptors could accelerate the developoment of AS;Livial could protect against the occuration and development of AS by increasing the mRNA expression of ER." @default.
- W2359302480 created "2016-06-24" @default.
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- W2359302480 date "2005-01-01" @default.
- W2359302480 modified "2023-09-25" @default.
- W2359302480 title "The Effect of Livial on Estrogen Receptor and Low-density Lipoprotein Receptor in Tissues of Atherosclerotic Rabbit" @default.
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