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- W2359337227 abstract "Objective To observe the clinical effect of biafine cream in preventing irradiation-induced skin injury of patients with nasopharyngeal carcinoma.Methods Eighty patients with nasopharyngeal carcinoma undergoing radiotherapy were randomly divided into 2 groups : 40 patients in the treatment group received a biafine cream application following the first radiotherapy, while 40 patients in the control group received no application of the cream, only followed normal procedures for conventional radiotherapy and health education.Results The irradiation-induced skin reaction occurred in both the treatment group and the control group.A mild radiation reaction ( grade- Ⅰ and Ⅱ ) occurred in 82.50% of patients ( 33/40 cases ) in the treatment group and 35% of patients ( 14/40 cases ) in the control group.A serve reaction (grade-Ⅲ and Ⅳ) occurred in 17.50% of patients (7/40 cases) in the treatment group and 65% of patients (26/40 cases) in the control group ( P 0.01 ).When the radiation dose was below 40Gy, the skin reaction occurred in 82.5% of patients(33/40) in the control group and in 37.5% of patients( 15/ 40) in the treatment group(P0.01).Conclusion Biafine cream can effectively prevent irradiative dermatitis and ensure uneventful radiotherapy." @default.
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- W2359337227 date "2010-01-01" @default.
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- W2359337227 title "Clinical effect of biafine cream in preventing irradiation-induced skin injury of patients with nasopharyngeal carcinoma" @default.
- W2359337227 hasPublicationYear "2010" @default.
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