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- W2359342017 abstract "Objective: To explore the clinical effect of rosuvastatin on inflammatory factors and cytokines in patients with acute coronary syndrome( ACS). Methods: 168 cases of ACS were divided into Atorvastatin( 56 cases),rosuvastatin 10 mg group( 56 cases) and 20 mg group( 56 cases). The plasma levels of inflammatory factors and cytokines were measured,and the occurrence rate of cardiovascular events were observed. Results: The levels of hs-CRP,TNF-a,and IL-6 in 20 mg group and in 10 mg group were significantly lower than those before treatment( P 0. 05),and it was the lowest in 20 mg group among three groups. Besides,the levels of VEGF and VCAM-1 in 20 mg group and 10 mg group were also significantly lower. The incidence of serious cardiovascular events in three groups had no difference after the treatment. Conclusion: Rosuvastatin can decrease the plasma levels of inflammatory factors and cytokines,reducing inflammation and stabilizing atherosclerotic plaque,thereby,reducing the incidence of serious cardiovascular event,and improving the situation of patients with ACS." @default.
- W2359342017 created "2016-06-24" @default.
- W2359342017 creator A5004302114 @default.
- W2359342017 date "2015-01-01" @default.
- W2359342017 modified "2023-09-23" @default.
- W2359342017 title "Effects of rosuvastatin on inflammatory factors and cytokines and cardiovascular events in patients with acute coronary syndrome" @default.
- W2359342017 hasPublicationYear "2015" @default.
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