Matches in SemOpenAlex for { <https://semopenalex.org/work/W2359368898> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2359368898 abstract "Objective:To evaluate the drug release in colon targeting of pH-triggered double layer colon target pellets of Sophora flavescens in vivo and in vitro.Method: Evaluate the drug release of the pellets in vitro with paddle method.Multi-slice spiral CT scanning was applied to detect the conveying of pellets in the digestive canal of human body in real time.Result: The pellets altogether released 26.18% of the drug in artificial gastric juice for two hours and in artificial intestinal juice for four hours,and accumulate to release 99.52% of the drug in artificial colon juice for two hours.The pellets were all emptied from stomach one hour after taking orally and all reached to colon after five hours.The disintegration of the pellets was not detected in stomach and small intestine,which started to disintegration after entering colon,disaggregated obviously after ten hours and completely disaggregated in colon after twenty-four hours.Conclusion: The pellets possess well drug release of colon targeting in vivo and in vitro." @default.
- W2359368898 created "2016-06-24" @default.
- W2359368898 creator A5084846204 @default.
- W2359368898 date "2011-01-01" @default.
- W2359368898 modified "2023-09-25" @default.
- W2359368898 title "Evaluation In vivo / in vitro of pH-triggered Double Layer Colon Target Pellets of Sophora flavescens" @default.
- W2359368898 hasPublicationYear "2011" @default.
- W2359368898 type Work @default.
- W2359368898 sameAs 2359368898 @default.
- W2359368898 citedByCount "0" @default.
- W2359368898 crossrefType "journal-article" @default.
- W2359368898 hasAuthorship W2359368898A5084846204 @default.
- W2359368898 hasConcept C150903083 @default.
- W2359368898 hasConcept C151730666 @default.
- W2359368898 hasConcept C185592680 @default.
- W2359368898 hasConcept C202751555 @default.
- W2359368898 hasConcept C207001950 @default.
- W2359368898 hasConcept C2776545273 @default.
- W2359368898 hasConcept C2778484605 @default.
- W2359368898 hasConcept C2779422922 @default.
- W2359368898 hasConcept C2780584874 @default.
- W2359368898 hasConcept C43617362 @default.
- W2359368898 hasConcept C55493867 @default.
- W2359368898 hasConcept C71924100 @default.
- W2359368898 hasConcept C86803240 @default.
- W2359368898 hasConcept C90924648 @default.
- W2359368898 hasConcept C98274493 @default.
- W2359368898 hasConceptScore W2359368898C150903083 @default.
- W2359368898 hasConceptScore W2359368898C151730666 @default.
- W2359368898 hasConceptScore W2359368898C185592680 @default.
- W2359368898 hasConceptScore W2359368898C202751555 @default.
- W2359368898 hasConceptScore W2359368898C207001950 @default.
- W2359368898 hasConceptScore W2359368898C2776545273 @default.
- W2359368898 hasConceptScore W2359368898C2778484605 @default.
- W2359368898 hasConceptScore W2359368898C2779422922 @default.
- W2359368898 hasConceptScore W2359368898C2780584874 @default.
- W2359368898 hasConceptScore W2359368898C43617362 @default.
- W2359368898 hasConceptScore W2359368898C55493867 @default.
- W2359368898 hasConceptScore W2359368898C71924100 @default.
- W2359368898 hasConceptScore W2359368898C86803240 @default.
- W2359368898 hasConceptScore W2359368898C90924648 @default.
- W2359368898 hasConceptScore W2359368898C98274493 @default.
- W2359368898 hasLocation W23593688981 @default.
- W2359368898 hasOpenAccess W2359368898 @default.
- W2359368898 hasPrimaryLocation W23593688981 @default.
- W2359368898 hasRelatedWork W1994416600 @default.
- W2359368898 hasRelatedWork W2010604256 @default.
- W2359368898 hasRelatedWork W2014496680 @default.
- W2359368898 hasRelatedWork W2050068056 @default.
- W2359368898 hasRelatedWork W2050608333 @default.
- W2359368898 hasRelatedWork W2060582408 @default.
- W2359368898 hasRelatedWork W2064941337 @default.
- W2359368898 hasRelatedWork W2094404921 @default.
- W2359368898 hasRelatedWork W2294226390 @default.
- W2359368898 hasRelatedWork W2315151387 @default.
- W2359368898 hasRelatedWork W2351749092 @default.
- W2359368898 hasRelatedWork W2364791939 @default.
- W2359368898 hasRelatedWork W2365134030 @default.
- W2359368898 hasRelatedWork W2366984736 @default.
- W2359368898 hasRelatedWork W2376458629 @default.
- W2359368898 hasRelatedWork W2380701508 @default.
- W2359368898 hasRelatedWork W2382221973 @default.
- W2359368898 hasRelatedWork W2387978209 @default.
- W2359368898 hasRelatedWork W2388251832 @default.
- W2359368898 hasRelatedWork W3134885822 @default.
- W2359368898 isParatext "false" @default.
- W2359368898 isRetracted "false" @default.
- W2359368898 magId "2359368898" @default.
- W2359368898 workType "article" @default.