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- W2359369569 abstract "Objective:To investigate the effects of pretreatment of tea pigment on the infarction size and myocardial cell injury in rabbits with acute cardiac ischemia. Methods:The left circumflex branch of rabbits coronary artery(LCX) was ligated to develop acute ischemic mode.The systolic and diastolic function of left ventricle (LV) was measured before and after ligating LCX, blood viscosity and hematocrit before and after ligating LCX were also measured.At 6 hour after LCX ligation, the hearts were harvested for determing the infarction size and evaluating TUNEL positive myocardial cell index.Results:①Tea pigment pretreatment significantly reduced the infarct size[(18.45±1.14)% vs (36.24±1.94)%, P 0.05],improve the LV function and viscosity of blood . ②TUNEL positive myocardial cell was found in the myocardium surrounding to the infarction area,however,the index of TP group was significantly lower than that of AI group [(28. 31±1.03)% vs (42.44±2.32)%, P 0.05] .Conclusion:Tea pigment pretreatment can reduce infarction size and TUNEL positive index ,and improve the LV function as well as blood viscosity in the acute ischemic mode." @default.
- W2359369569 created "2016-06-24" @default.
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- W2359369569 date "2001-01-01" @default.
- W2359369569 modified "2023-09-22" @default.
- W2359369569 title "Effects of Tea Pigment Pretreatment on the Infarct Size and Myocardial Cell Injury in Rabbit" @default.
- W2359369569 hasPublicationYear "2001" @default.
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