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- W2359394778 abstract "Objective To study the effects of manganese in urine,lipid peroxidation,antioxidant enzymes and acetylcholinesteraes(AChE) activity in welders exposed to manganese dust.Methods 384 workers exposed to manganese and 211 non-exposure controls were investigated.Urine manganese contents,serum malondialdehyde(MDA),activities of superoxide dismutase(SOD),glutathione peroxidase(GSH-Px) and AChE were detected.Results The contents of urine manganese,MDA and the activity of AChE were significantly increased in the exposed group,compared with those in the control(P0.01).The activities of SOD and GSH-Px were significantly lower in the exposed workers(P0.01).A dose-effect relationship existed between the contents of MDA and air-manganese.With the increase of the working age,the contents of MDA increased but the activities of SOD decreased,compared with those of the group of 10 years exposure(P0.05).Conclusion Manganese dust increased the contents of lipid peroxidation products and the activities of AChE,and decrease the activities of antioxidant enzymes in exposed workers.MDA and SOD may be used as the early sensitive indexes of manganism poisoning and effect biomarkers." @default.
- W2359394778 created "2016-06-24" @default.
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- W2359394778 date "2009-01-01" @default.
- W2359394778 modified "2023-09-26" @default.
- W2359394778 title "Effects of manganese dust on serum lipid peroxidation,antioxidant enzymes and acetylcholinesteraes activity in welders" @default.
- W2359394778 hasPublicationYear "2009" @default.
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