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- W2359398018 abstract "Objective To perform cortical functional mapping by means of electrical cortical stimulation,and to compare the differences of threshold for afterdischarges(ADs) among anatomical lobes as well as to correlate its threshold with epileptogenic zone localizaiton.Methods To implant subdural electrode strips or grids over the most possible areas of epileptogenic zone(EZ) determined by the integral information analysis of scalp vedio-electroencephalography(VEEG),MRI,SPECT and PET in 7 patients with intractable epilepsy.To accomplish the cortical functional mapping using electrical cortical stimulation with constan current stimulus,and to compare the differences of threshold for afterdischarge among fronal,parietal-occipital and temporal lobes as well as to explore its value for EZ localizaiton.Results EZ was located in the frontal lobe in 3 cases,parietal lobe in 1 cases,occipital lobe in 1 case and temporal lobe in 2 case.Differences of threshold for cortical mapping between adjacent electrods within the frontal,parietal-occipital and temporal lobes were 11,4 and 4.5 mA,respectively.No significant difference was found among the these cortical areas(P=0.685).AD threshold in temporal lobe was statistically lower than those in frontal and parietal-occipital regions(P=0.015).ADs mostly occurred within the areas 2-3 cm around the EZ with strong rhythm and high amplitude when EZ were stimulated.However,ADs scatterd among the different places with relatively weak rhythm and low amplitude when non-EZ were stimulated.When EZ was located or closed to the eloquent cortex,the cortex with relatively lower AD threshold were selectively operated.No obvious or permanent neurological deficit was remained,the outcome for seizure control was good according Engel'classification scale.Conclusion ADs and electrical cortical stimulation would help to localize the EZ focu,improve the surgical outcome,and decrease the postoperative disability." @default.
- W2359398018 created "2016-06-24" @default.
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- W2359398018 date "2012-01-01" @default.
- W2359398018 modified "2023-09-26" @default.
- W2359398018 title "Primary study on electrical cortical stimulation mapping and threshold for afterdischarges" @default.
- W2359398018 hasPublicationYear "2012" @default.
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