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- W2359405412 abstract "AIM: To study the expression profile of QKI m RNA and protein in rat heart during pathological cardiac hypertrophy. ME THODS: A rat cardiac hypertrophy model was established using continuous norepinephrine (NE) perfusion. Real-time PCR and Western blotting were applied t o examine QKI mRNA and protein expression respectively in rat heart. RES ULTS: Both mRNA and protein of three QKI isoforms were detected in adult rat heart. QKI-5 mRNA and total QKI protein were remarkably decreased in NE-ind uced hypertrophic heart compared with those in control group (P0 05). Furt hermore, the expression of QKI-5 mRNA also appeared to be lower than those in co ntrol group when the neonatal rat cardiomyocytes were incubated with NE. C ONCLUSION: Three QKI isoforms express in rat heart and they may particip ate in cardiac hypertrophy." @default.
- W2359405412 created "2016-06-24" @default.
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- W2359405412 date "2004-01-01" @default.
- W2359405412 modified "2023-09-22" @default.
- W2359405412 title "Expression of STAR protein QKI in norepinephrine-induced rat cardiac hypertrophy" @default.
- W2359405412 hasPublicationYear "2004" @default.
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