FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2359416365> ?p ?o ?g. }

• W2359416365 abstract "Isopropyl p-toluenesulfonate (IPTS) is a potentially genotoxic by-product formed during the esterification of palm oil-based palmitic and palm kernel oil-based myristic acid with isopropanol to produce isopropyl palmitate or isopropyl myristate. There are no methods described for the analysis of IPTS in cosmetic products. In this work, we have established a simple, precise and accurate method to determine the presence and level of IPTS in various finished cosmetic products which contain palm-based esters in their formulations.An Agilent 1200 series high-performance liquid chromatography (HPLC) unit using a diode-array detector (DAD) has been employed and optimized to detect IPTS in cosmetic products. For the separation, a reverse-phase Hypersil Gold C8 column (5 μm, 4.6 mm i.d. 250 mm) 5 mM tetrabutylammonium phosphate buffer 50 : 50, (v/v) solution in acetonitrile as mobile phase, in isocratic mode and a flow rate of 0.8 mL min-1 were used. A second method using a gas chromatography/mass selective detector GC-MSD was also developed to confirm the IPTS identity in the cosmetic products.Recoveries of IPTS from cosmetic matrices such as a lotion, cleansing milk and a cream ranged from 94.0% to 101.1% with <5% relative standard deviation (%RSD) showing good accuracy and repeatability of the method. The six-point calibration curves (determined over the range 0.5-50 μg mL-1 ) have a correlation coefficient of 0.9999 (based on HPLC peak area) and 0.9998 (based on HPLC peak height). The intra- and interday precisions (measured by the %RSD) of the method were <2% and <5%, respectively, indicating that the developed method is reliable, precise and reproducible. The detection and quantification limit of the method were found to be 0.5 μg mL-1 and 1.6 μg mL-1 , respectively. Analyses of 83 commercial cosmetics showed no presence of IPTS.The validation data indicated that this method was suitable for the quantitative analysis of IPTS in commercial cosmetics. This method is applicable for analyses of trace levels of IPTS in cosmetics and has the advantage of using only simple sample preparation steps." @default.
• W2359416365 created "2016-06-24" @default.
• W2359416365 creator A5023069728 @default.
• W2359416365 creator A5026831688 @default.
• W2359416365 creator A5032975849 @default.
• W2359416365 date "2016-06-30" @default.
• W2359416365 modified "2023-09-26" @default.
• W2359416365 title "Determination and confirmation of isopropyl p-toluenesulfonate in cosmetics by HPLC-diode array detector method and GC-MS" @default.
• W2359416365 cites W1964915638 @default.
• W2359416365 cites W1973834691 @default.
• W2359416365 cites W1977261074 @default.
• W2359416365 cites W1979985161 @default.
• W2359416365 cites W1985422052 @default.
• W2359416365 cites W2024429336 @default.
• W2359416365 cites W2027380183 @default.
• W2359416365 cites W2034100531 @default.
• W2359416365 cites W2041464495 @default.
• W2359416365 cites W2044632961 @default.
• W2359416365 cites W2046809863 @default.
• W2359416365 cites W2059036678 @default.
• W2359416365 cites W2070904110 @default.
• W2359416365 cites W2073155598 @default.
• W2359416365 cites W2086753477 @default.
• W2359416365 cites W2102250394 @default.
• W2359416365 cites W4205500195 @default.
• W2359416365 cites W4211150061 @default.
• W2359416365 cites W4233617542 @default.
• W2359416365 cites W4255499789 @default.
• W2359416365 doi "https://doi.org/10.1111/ics.12342" @default.
• W2359416365 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27169828" @default.
• W2359416365 hasPublicationYear "2016" @default.
• W2359416365 type Work @default.
• W2359416365 sameAs 2359416365 @default.
• W2359416365 citedByCount "2" @default.
• W2359416365 countsByYear W23594163652020 @default.
• W2359416365 countsByYear W23594163652021 @default.
• W2359416365 crossrefType "journal-article" @default.
• W2359416365 hasAuthorship W2359416365A5023069728 @default.
• W2359416365 hasAuthorship W2359416365A5026831688 @default.
• W2359416365 hasAuthorship W2359416365A5032975849 @default.
• W2359416365 hasConcept C104264131 @default.
• W2359416365 hasConcept C110084920 @default.
• W2359416365 hasConcept C154020017 @default.
• W2359416365 hasConcept C15761196 @default.
• W2359416365 hasConcept C178790620 @default.
• W2359416365 hasConcept C179998833 @default.
• W2359416365 hasConcept C185592680 @default.
• W2359416365 hasConcept C2775850501 @default.
• W2359416365 hasConcept C2776918747 @default.
• W2359416365 hasConcept C2777463227 @default.
• W2359416365 hasConcept C2779717098 @default.
• W2359416365 hasConcept C2779783494 @default.
• W2359416365 hasConcept C43617362 @default.
• W2359416365 hasConceptScore W2359416365C104264131 @default.
• W2359416365 hasConceptScore W2359416365C110084920 @default.
• W2359416365 hasConceptScore W2359416365C154020017 @default.
• W2359416365 hasConceptScore W2359416365C15761196 @default.
• W2359416365 hasConceptScore W2359416365C178790620 @default.
• W2359416365 hasConceptScore W2359416365C179998833 @default.
• W2359416365 hasConceptScore W2359416365C185592680 @default.
• W2359416365 hasConceptScore W2359416365C2775850501 @default.
• W2359416365 hasConceptScore W2359416365C2776918747 @default.
• W2359416365 hasConceptScore W2359416365C2777463227 @default.
• W2359416365 hasConceptScore W2359416365C2779717098 @default.
• W2359416365 hasConceptScore W2359416365C2779783494 @default.
• W2359416365 hasConceptScore W2359416365C43617362 @default.
• W2359416365 hasFunder F4320328606 @default.
• W2359416365 hasLocation W23594163651 @default.
• W2359416365 hasLocation W23594163652 @default.
• W2359416365 hasOpenAccess W2359416365 @default.
• W2359416365 hasPrimaryLocation W23594163651 @default.
• W2359416365 hasRelatedWork W2019590687 @default.
• W2359416365 hasRelatedWork W2037191186 @default.
• W2359416365 hasRelatedWork W2085491095 @default.
• W2359416365 hasRelatedWork W2090393754 @default.
• W2359416365 hasRelatedWork W2351506579 @default.
• W2359416365 hasRelatedWork W2359416365 @default.
• W2359416365 hasRelatedWork W2389150922 @default.
• W2359416365 hasRelatedWork W2389554097 @default.
• W2359416365 hasRelatedWork W2462726270 @default.
• W2359416365 hasRelatedWork W3028740714 @default.
• W2359416365 isParatext "false" @default.
• W2359416365 isRetracted "false" @default.
• W2359416365 magId "2359416365" @default.
• W2359416365 workType "article" @default.