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- W2359429598 abstract "Objective To clarify the renal excretion mechanism of 99 Tc m BPHA and the possibility of its clinical application. Methods The renal excretion mechanism was determined by probenecid inhibition experiment. The radioactivity remained in the body at different time points post injection was determined by a γ ray determination apparatus equipped with a lead chamber. Renal dynamic imaging with 99 Tc m BPHA was performed on 4 rabbits and 1 normal volunteer using a γ camera. For all the experiments, 99 Tc m DTPA was also examined as a control agent. Results Similar to 99 Tc m DTPA, 99 Tc m BPHA was excreted with a glomerular excretion mechanism. The excretion was fast. After 24 h, 99 Tc m BPHA remained in the body was very little. Kidney imaging of the rabbits and the volunteer showed excellent kidney images and fast 99 Tc m BPHA excretion. Conclusions Self made 99 Tc m BPHA is a glomerular imaging agent satisfying clinical requirements, and it is a promising alternative to 99 Tc m DTPA." @default.
- W2359429598 created "2016-06-24" @default.
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- W2359429598 date "2001-01-01" @default.
- W2359429598 modified "2023-09-27" @default.
- W2359429598 title "The renal function imaging with ~(99)Tc~m-BPHA and renal excretion mechanism of the agent" @default.
- W2359429598 hasPublicationYear "2001" @default.
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