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- W2359431444 abstract "Objective To investigate the clinical and functional features of non-erosive reflux disease (NERD).Methods 74 cases of GERD were divided into two groups according to the endoscopic findings and results of simultaneous 24-hour esophageal pH and bilirubin monitoring: NERD(n=36) and reflux esophagitis(RE)(n=38).The general conditions, endoscopic findings and esophageal motility were compared between two groups.Results Significant difference were found in the frequency of hiatal herma and sex distribution. But no significant difference was found in acid reflux. The index values of duodenogastroesophageal reflux (DGER) in NERD group such as percent of time with Abs0.14, 5min reflux times were 8.6±11.8, 3.0±3.8 respectively, they were significantly lower than those of RE, 17.1±22.2, 5.4+6.0 respectively (P0.05). But the amplitude of distal waves was higher than that of RE patients (P0.05) .Conclusion The differences of clinical and esophageal functional features exist between patients with NERD and RE. DGER is more common and severe in reflux esophagitis. These findings maybe suggest the different underlying pathophysiology of NERD." @default.
- W2359431444 created "2016-06-24" @default.
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- W2359431444 date "2004-01-01" @default.
- W2359431444 modified "2023-09-23" @default.
- W2359431444 title "A preliminary investigation of the clinical and functional features of non-erosive reflux disease" @default.
- W2359431444 hasPublicationYear "2004" @default.
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