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- W2359432973 abstract "Objective To study the application value of hepatitis C virus RNA detection(PCR-fluorescent probe) and hepatitis C virus antibody detection(ELISA,anti-HCV) in the diagnosis of hepatitis C.Methods The HCV-RNA and anti-HCV tests of 265 suspected HCV patients were reviewed,statistics of anti-HCV and HCV-RNA detection results and ALT level in different ages and gender was collected and analysized.Results ①Anti-HCV and HCV-RNA positive rates in men were higher than those in women,but there was no statistically significant difference(P 0.05).② Anti-HCV and HCV-RNA positive rates in 40 years old patients were obviously higher than those in ≤40 years old patients,with statistically significant difference(P 0.05);ALT abnormal rates also had significant difference between 40 and ≤40 years old patients(P 0.05).③ ALT abnormal rate increased with increasing HCV-RNA positive rate and have positive correlation with HCV-RNA content(r = 0.999,P 0.05).But the ALT levels did not correlate with HCV-RNA content(r = 0.800,P 0.05).④The abnormal rate of Anti-HCV was closely correlated with HCV-RNA(r = 0.320);Anti-HCV,HCV-RNA and ALT had no statistically significant difference(P 0.05).Conclusions ①Anti-HCV and HCV-RNA detection have no relation with gender,but they have certain relevance with age.②ELISA for detecting anti-HCV is still first choice in HCV.Combined use of HCV-RNA,anti-HCV and ALT detection,will be the most reliable and valuable method in diagnosis of HCV." @default.
- W2359432973 created "2016-06-24" @default.
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- W2359432973 date "2013-01-01" @default.
- W2359432973 modified "2023-09-25" @default.
- W2359432973 title "Retrospective analysis of Antibody of HCV and quantification of HCV RNA in diagnosis of hepatitis C" @default.
- W2359432973 hasPublicationYear "2013" @default.
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