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- W2359453432 abstract "Objective The aim of this study was to describe the interdigestive gastroduodenal motility in patients with decompensated cirrhosis. Methods The interdigestive gastroduodenal motility was detected by means of perfused gastrointestinal motility manometer in fifteen healthy subjects and twelve decompensated cirrhotic patients. Results The mean duration of both MMC (migrating motor complex) phaseⅠand phaseⅡin patients with cirrhosis was not different from that of controls (P0.05). However, phaseⅡwas significantly longer in cirrhotic patients in comparison with controls(P0.01).The duration of MMC was also significantly prolonged in patients with cirrhosis as compared with controls (P0.01). Furthermore, multiple clusters of contractions separated by quiescent periods during duodenal phase Ⅱ were more often observed in patients with cirrhosis(P0.05). Conclusion We concluded that the prolonged duration of MMC was caused by a longer phase Ⅱ in patients with cirrhosis. The prolonged duration of MMC results in decreased frequency of phase Ⅲ, which may cause an impairment of the main mechanism responsible for sweeping the small bowel content. The lack of motor activity between clusters observed in phase Ⅱ might be associated with delayed intestinal transit." @default.
- W2359453432 created "2016-06-24" @default.
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- W2359453432 date "2007-01-01" @default.
- W2359453432 modified "2023-09-26" @default.
- W2359453432 title "Interdigestive gastroduodenal motility in decompensated liver cirrhosis" @default.
- W2359453432 hasPublicationYear "2007" @default.
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