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- W2359465274 abstract "Objective To investigate the quantitative change of interstitial cells of Cajal(ICC) in rats bladder with detrusor hyperreflexia or detrusor areflexia after spinal cord injury and explore the relationship between the function changes of detrusor of bladder and ICC.Methods Forty rats were randomly divided into normal group,post-cystostomy bladder group,detrusor hyperreflexia bladder group and detrusor areflexia bladder group,ten rats in each group.The rats models with suprasacral cord injury and sacral cord injury were made,and urodynamic studies were conducted to confirm that bladder respectively expressed detrusor hyperreflexia and detrusor areflexia,then specimens of rats bladder were stained immunohistochemically with a c-kit antibody,and the number of ICC was observed with a laser confocal microscope.Results There was no statistic difference in the number of ICC between normal group and post-cystostomy group(P 0.05).The number of ICC was significantly higher in detrusor hyperreflexia bladder group than that in normal and post-cystostomy bladder group(P0.05).The number of ICC was significantly lower in detrusor areflexia bladder group than that in normal and post-cystostomy bladder group(P0.05).Conclusion It is possible that the function changes of bladder after spinal cord injury may be related to changes of the number of ICC." @default.
- W2359465274 created "2016-06-24" @default.
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- W2359465274 date "2009-01-01" @default.
- W2359465274 modified "2023-09-24" @default.
- W2359465274 title "Quantitative change of interstitial cells of Cajal in rats bladder with detrusor hyperreflexia or detrusor areflexia" @default.
- W2359465274 hasPublicationYear "2009" @default.
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