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- W2359484724 abstract "Objective To investigate the effects of flunarizine on change of the serum transforming growth factor-β1 in patients with ischemic cerebral infarction.Methods Sixty patients with acute cerebral infarction were divided randomly into two groups:flunarizine group treated with flunarizine at the 2nd after stroke and 30 age-matched controls were enrolled in this study.The serum levels of TGF-β1 in of both groups were determined by ELISA at the 1st、3rd、7th day and 14th after stroke.Results The levels of serum TGF-β1 in the patients with ischemic cerebral infarction were significantly lower at the 1st day than that in healthy controls(P0.01).The serum TGF-β1 levels in the patients of flunarizine group were significantly higher at the 3rd、7th and 14th day than that of control group(P0.01).Conclusion Flunarizine may be advantageous to the signal transduction of TGF-β1,and enhance the level of serum TGF-β1,and may protected brain tissue from injury caused by ischemic reperfusion." @default.
- W2359484724 created "2016-06-24" @default.
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- W2359484724 date "2007-01-01" @default.
- W2359484724 modified "2023-09-28" @default.
- W2359484724 title "Impact of flunarizine on changes of serum transforming growth factor-β_1 in patients with cerebral infarction" @default.
- W2359484724 hasPublicationYear "2007" @default.
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