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- W2359542770 abstract "Objective To observe the protein and the mRNA expression of gonadotropin-releasing hormone(GnRH)and its receptor(GnRH-R)in endometrium of patients with endometriosis and to investigate its significance.Methods Protein expression and localization of GnRH and GnRH-R from endometriosis eutopic and ectopic endometrium of patients with endometriosis and in normal endometrium of cortrol subjects were analyzed by immunohistochemistry.mRNA expressions were observed by reverse transcription(RT)-polymerase chain reaction(PCR)method.Results GnRH and GnRH-R were expressed at the protein and mRNA level in all eutopic and normal endometrium,and in approximately 50% of ectopic endometrium.Conclusions There exist protein and mRNA expressions of GnRH and its receptor in endometrium of patients with endometriosis,indicating that GnRH-R can be target of GnRH analogs used in clinical treatment." @default.
- W2359542770 created "2016-06-24" @default.
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- W2359542770 date "2008-01-01" @default.
- W2359542770 modified "2023-09-27" @default.
- W2359542770 title "Expression and significance of GnRH and its receptors in endometrium of patients with endometriosis" @default.
- W2359542770 hasPublicationYear "2008" @default.
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