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- W2359565031 abstract "OBJECTIVE To investigate of the dissolution results in virtro of low-dose aspirin enteric-coated drugs from six manufactures and provide suggestions for clinical use.METHODS The dissolution tests were carried out in dissolution test system with the rotating basket of Pharmacopoeia of People′s Republic of China.The T50,Td and m value were figured out by the Weibull′s equation,and similarity for dissolution profiles were evaluated by f2 factor.RESULTS T50 and Td of drugs from manufacturers D、E and F was smaller,and there were significant differences in between drugs from manufacturer A(made by Bayer Schering Pharma Ltd.);Compared with the A,the similarity factors of the drugs from manufacturers B、C、D、Eand F were 42,52,28,29 and 31,respectively.CONCLUSION The dissolution results of six kinds of aspirin drugs all met with the requirements of the Pharmacopoeia.The dissolution characteristics for product from manufacturer C was similar to Bayer Schering Pharma Ltd." @default.
- W2359565031 created "2016-06-24" @default.
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- W2359565031 date "2011-01-01" @default.
- W2359565031 modified "2023-09-24" @default.
- W2359565031 title "Comparison of dissolution profiles of low-dose aspirin enteric-coated drugs from different manufactures" @default.
- W2359565031 hasPublicationYear "2011" @default.
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