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- W2359571743 abstract "Objective: To investigate the direct central protective effect of insulin on changes of memory of rat after global brain ischemia. Methods: The 1U/kg of insulin was administered to the rat intraperitoneally after reperfusion immediatelly. Eight weeks post brain ischemia, the ability of memory of rat was tested by Y maze, and the number of normal neurons was counted. Results: The memory of rats ischemic-group was greatly damaged. The number of normal neurons in the CA1 region was hight significant in the treated-group. Conclusion: Insulin administered post global brain ischemia can attenuate the memory deficits of rats, and this effect bases on reducing the necrosis of neurons in the hippocampal CA1 region. It has a direct neuroprotective effect on global bran ischemia." @default.
- W2359571743 created "2016-06-24" @default.
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- W2359571743 date "2000-01-01" @default.
- W2359571743 modified "2023-09-25" @default.
- W2359571743 title "The effect of insulin on memory of rat after global brain ischemia" @default.
- W2359571743 hasPublicationYear "2000" @default.
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