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- W2359616585 abstract "Objectives To study changes of plasma adiponectin, plasminogen activator inhibitor levels in patients with coronary heart disease and to investigate its clinical implications. Methods Coronary heart disease(n=151)and health control group (n=50) were selected. Coronary heart disease group were divided into stable angina pectoris group(n=47),unstable angina pectoris group(n=50)and acute myocardialinfarction (n=54). Plasma concentration of adiponectin and PAI-1 were measured by emzyme-linked immunosorbent assay(ELISA). Results ①Plasma concentrations of adiponectin(ug/ml): coronary heart disease group(5.3±2.1) were significantly lower than health control group(7.8±2.2,P0.01); there were no differences between SA group(7.2±1.7) and health control group(P0.05); UA group (4.7±1.7) were significantly lower than health control group and SA group (P0.01); AMI group (4.2±1.7) were significantly lower than health control group and SA group(P0.01); ②Plasma concentrations of PAI-1(U/L): coronary heart disease group(48±25)were significantly higher than health control group(20±13, P0.01); there were no differences between SA group(26±14) and health control group(P0.05); UA group(54±21)were significantly higher than health control group and SA group(P0.01); AMI group(60±24)were significantly higher than health control group and SA group(P0.01);③The coefficient correlation of plasma concentrations of adiponectin and PAI-1 were -0.641(P0.01). Conclusions ①Low adiponectin level possibly is one of etiological factors of coronary heart disease,and plasma adiponectin levels possibly reflect plaque stability of coronary heart disease;②Low adiponectin levels possibly participate ACS development through degrading fibrinolytic function." @default.
- W2359616585 created "2016-06-24" @default.
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- W2359616585 date "2006-01-01" @default.
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- W2359616585 title "Relationship between plasma adiponectin levels and fibrinolytic activities in patients with coronary heart disease" @default.
- W2359616585 hasPublicationYear "2006" @default.
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