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- W2359619720 abstract "Objective To explore the relationship between the cerebral infarction and the angiotensinogen(AGT)gene rs699 polymorphism and the concentration of AGT in plasma in Tianjin,China.Methods Eighty nine patients with acute cerebral infarction in Tianjin Beichen District Chinese Medical Hospital from January to October 2011 were involved in this study.Eigthy-two healthy person who received physical examination were chosen as control group.AGT rs699 gene polymorphism was examined by gene sequence method.Plasma AGT concentration was determined by enzyme-linked immunosorbent assay(ELISA)method.Results There was no relationship between the cerebral infarction and AGT gene rs699polymorphism,but the plasma AGT level of the acute cerebral infarction patients[(273.53 ± 38.21)ng / ml]was much higher than the control subjects[(164.59 ± 44.54)ng / ml].There was no significant difference between three different genotypes of AGT either in acute cerebral infarction group or control group.Conclusions AGT rs699 gene polymorphism has no relationship with acute cerebral infarction,while the plasma AGT levels has the significant relationship in Tianjin,which is independent with rs699 gene polymorphism,which indicates the high concentration of AGT should be the risk factor for the cerebral infarction in Tianjin area." @default.
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- W2359619720 date "2012-01-01" @default.
- W2359619720 modified "2023-09-23" @default.
- W2359619720 title "Relationship between angiotensinogen gene polymorphism and its levels in plasma with acute cerebral infarction" @default.
- W2359619720 hasPublicationYear "2012" @default.
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