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- W2359634534 abstract "Objective To detect the expression of survivin,galectin-3 and Ki-67 protein,and to evaluate their correlations in breast cancer and adjacent normal tissues. Methods The expression of survivin,galectin-3 and Ki-67 in breast cancer tissues( 120 cases) and adjacent normal tissues( 120 cases) were detected by immunohistochemical SP method.Results The positive rate of survivin expression in breast cancer tissues( 70. 83%) was higher than that in adjacent normal tissues( 5. 00%)( P 0. 05),and was correlated with node metastasis. There were no correlations between the expression o f survivin and the histological grade. The expression of galectin-3 and Ki-67 in breast cancer tissues was also significantly higher than that in adjacent normal tissues. In addition,the expression of galectin-3 and Ki-67 was correlated with the pathological grade and node metastasis. The expression of survivin was positively correlated with galectin-3 and Ki-67 expression. Conclusion Survivin,galectin-3 and Ki-67 proteins may play synergetic roles in the process of carcinogenesis of breast cancer,meanwhile,they may play an important role in the carcinogenesis and progress of breast cancer through the inhibition of apoptosis." @default.
- W2359634534 created "2016-06-24" @default.
- W2359634534 creator A5061363908 @default.
- W2359634534 date "2013-01-01" @default.
- W2359634534 modified "2023-09-24" @default.
- W2359634534 title "Expression and significance of survivin,galectin-3 and Ki-67 in breast cancer" @default.
- W2359634534 hasPublicationYear "2013" @default.
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