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- W2359647683 abstract "AIM: To establish a mouse model of upper respiratory tract mucosal immunity dysfunction induced by cold stimulation.METHODS: Mice were stimulated with cold by placing the animals in-20 ℃ environment for 5 min,10 min,15 min or 20 min.The secretory immunoglobulin A(SIgA) level and lysozyme activity in the mouse saliva were determined for qualification.RESULTS: The mortality rate was 50% in the group of cold stimulation for 20 min.Compared with the control mice,the SIgA level and lysozyme activity significantly decreased in the group of cold stimulation for 15 min(P0.05 and P0.01,respectively).Decreased lysozyme activity was only observed in the group of cold stimulation for 10 min(P0.05).The data in the group of cold stimulation for 5 min were almost similar to those in control group.CONCLUSION: A mouse model of upper respiratory tract mucosal immunity dysfunction was successfully established by cold stimulation." @default.
- W2359647683 created "2016-06-24" @default.
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- W2359647683 date "2011-01-01" @default.
- W2359647683 modified "2023-09-24" @default.
- W2359647683 title "A mouse model of upper respiratory tract mucosal immunity dysfunction induced by cold stimulation" @default.
- W2359647683 hasPublicationYear "2011" @default.
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