Matches in SemOpenAlex for { <https://semopenalex.org/work/W2359659715> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2359659715 abstract "Objective:To investigate the effect of Laurencia terpenoid extract (LET) on tumor inhibition,immune modulation and apoptosis of Sarcoma 180 cell. Method:The LD50 of LET was estimated by Horn assay. The models of S180-bearing mice were established and divided into 4 groups which were given LET 0 (control group), 25 (low-dose group), 50 (mid-dose group), 100 (high-dose group) mg/kg bw respectively for 10 d. Tumor inhibition rates were detected in treatment groups and control group respectively. To weigh exactly the thymus and spleen to calculate their indices. The proliferation effect of LET on spleen lymphocyte was evaluated by MTT assay. The apoptosis of tumor cell was assayed by flow cytometry. Results:The LD50 was more than 3 160 mg/kg bw. LET had low toxicity. The average tumor weights of the supplemented groups were all less than the control group(P0.05). The tumor inhibition rate of the high-dose group was 39.1%. Mid-dose LET obviously increased the level of thymus index. High-dose LET obviously increased the level of spleen index. LET increased the multiplication of spleen lymph cells. Apoptosis of S180 of supplemented groups was significantly higher than the control group (P0.05). Conclusion:LET is safe and can strengthen the immune system, and induce apoptosis of S180 cells,increase of cells in G0/G1 phase and decrease in S phase." @default.
- W2359659715 created "2016-06-24" @default.
- W2359659715 creator A5036935617 @default.
- W2359659715 date "2005-01-01" @default.
- W2359659715 modified "2023-09-24" @default.
- W2359659715 title "THE ANTICANCER ACTIVITIES AND MECHANISM OF LAURENCIA TERPENOIDS EXTRACT" @default.
- W2359659715 hasPublicationYear "2005" @default.
- W2359659715 type Work @default.
- W2359659715 sameAs 2359659715 @default.
- W2359659715 citedByCount "0" @default.
- W2359659715 crossrefType "journal-article" @default.
- W2359659715 hasAuthorship W2359659715A5036935617 @default.
- W2359659715 hasConcept C153911025 @default.
- W2359659715 hasConcept C185592680 @default.
- W2359659715 hasConcept C190283241 @default.
- W2359659715 hasConcept C203014093 @default.
- W2359659715 hasConcept C206103511 @default.
- W2359659715 hasConcept C2780931953 @default.
- W2359659715 hasConcept C553184892 @default.
- W2359659715 hasConcept C55493867 @default.
- W2359659715 hasConcept C86803240 @default.
- W2359659715 hasConcept C8891405 @default.
- W2359659715 hasConcept C98274493 @default.
- W2359659715 hasConceptScore W2359659715C153911025 @default.
- W2359659715 hasConceptScore W2359659715C185592680 @default.
- W2359659715 hasConceptScore W2359659715C190283241 @default.
- W2359659715 hasConceptScore W2359659715C203014093 @default.
- W2359659715 hasConceptScore W2359659715C206103511 @default.
- W2359659715 hasConceptScore W2359659715C2780931953 @default.
- W2359659715 hasConceptScore W2359659715C553184892 @default.
- W2359659715 hasConceptScore W2359659715C55493867 @default.
- W2359659715 hasConceptScore W2359659715C86803240 @default.
- W2359659715 hasConceptScore W2359659715C8891405 @default.
- W2359659715 hasConceptScore W2359659715C98274493 @default.
- W2359659715 hasLocation W23596597151 @default.
- W2359659715 hasOpenAccess W2359659715 @default.
- W2359659715 hasPrimaryLocation W23596597151 @default.
- W2359659715 hasRelatedWork W2352476184 @default.
- W2359659715 hasRelatedWork W2353049907 @default.
- W2359659715 hasRelatedWork W2359917672 @default.
- W2359659715 hasRelatedWork W2362275215 @default.
- W2359659715 hasRelatedWork W2362627706 @default.
- W2359659715 hasRelatedWork W2368179753 @default.
- W2359659715 hasRelatedWork W2371521203 @default.
- W2359659715 hasRelatedWork W2377542558 @default.
- W2359659715 hasRelatedWork W2378024348 @default.
- W2359659715 hasRelatedWork W2378928731 @default.
- W2359659715 hasRelatedWork W2379723340 @default.
- W2359659715 hasRelatedWork W2385248283 @default.
- W2359659715 hasRelatedWork W2385524330 @default.
- W2359659715 hasRelatedWork W2389301545 @default.
- W2359659715 hasRelatedWork W2389927607 @default.
- W2359659715 hasRelatedWork W2392366295 @default.
- W2359659715 hasRelatedWork W2393505874 @default.
- W2359659715 hasRelatedWork W2410072528 @default.
- W2359659715 hasRelatedWork W3029624284 @default.
- W2359659715 hasRelatedWork W3029853494 @default.
- W2359659715 isParatext "false" @default.
- W2359659715 isRetracted "false" @default.
- W2359659715 magId "2359659715" @default.
- W2359659715 workType "article" @default.