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- W2359690623 abstract "Telomere is an important DNA-protein structure.It caps the ends of linear eukaryotic chromosomes.Telomeric DNA consists of tandemly repeated simple sequences.Telomere is synthesized with the action of telomerase,a ribonucleoprotein with reverse transcriptase activity.Telomere plays an important role in maintaining the stability of intact chromosome,genome and cell.Telomerase is a ribonucleoprotein responsible in most eukaryotes for replication of the end of chromosomes.Its RNA subunit acts as a template for the systhesis of telomeric DNA,while a protein component catalyzes this process to make up for convertional DNA polymerases’ inability to replicate completely the end linear DNA.It belongs to the reverase transcriptase family but differs from reverse transcriptase.The overexprossion of telomerase has close relationship with cell’s immortalization and tumorigenesis.The structure and function of telomerase suggest its extensive application in the near future." @default.
- W2359690623 created "2016-06-24" @default.
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- W2359690623 date "2005-01-01" @default.
- W2359690623 modified "2023-09-24" @default.
- W2359690623 title "Structure,Function and Application of Telomere and Telomerase" @default.
- W2359690623 hasPublicationYear "2005" @default.
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