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- W2359704189 abstract "Aim To investigate the effect of ATP on the basolateral K + channels in the thick ascending limb(TAL) of rat kidney.Methods The single channel patch-clamp technique was used to record the basolateral K + channel current in the TAL,and channel open probability was calculated before and after the addition of ATP.Results 1mmol·L -1 ATP inhibited 50 pS K + channels in basolateral membrane of TAL in insideout patches,and channel open probability was decreased from 0.46±0.28 to 0.02±0.04 after addition of ATP.The inhibitory effect of ATP on 50 pS K + channels was dose-dependent.Conclusion The activity of K + channel in basolateral membrane of TAL is regulated by cellular ATP." @default.
- W2359704189 created "2016-06-24" @default.
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- W2359704189 date "2010-01-01" @default.
- W2359704189 modified "2023-09-25" @default.
- W2359704189 title "Effect of ATP on activity of 50 pS K~+ channel in basolateral membrane of the thick ascending limb" @default.
- W2359704189 hasPublicationYear "2010" @default.
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