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- W2359717565 abstract "Objective To observe the effects of acute hypervolemic hemodilution(AHH)combined with urapidil-induced controlled hypotension on hemodynamics,tissue perfusion,blood loss and blood transfusion in surgery. Methods Forty-eight ASAⅠ-Ⅱpatients undergoing elective operation of spinal surgery were randomly divided into control group(groupⅠ,n=16),AHH group(groupⅡ,n=16)and AHH combined with urapidil-induced controlled hypotension group(group Ⅲ,n=16).Mean aortic pressure(MAP),central venous pressure(CVP),heart rate(HR),haematocrit(Hct),hemoglobin(Hb)and blood lactate were recorded before hemo-diluion(T0,the time after induction of anesthesia in groupⅠ),at 30 min after hemodilution(T1,the time after induction of anesthesia for 30 min in groupⅠ),and at 1 h after hemodilution(T2).Urine output,blood loss and blood transfusion were recorded during operation. Results There was no significant change in HR and blood lactate between and within 3 groups(P0.05).CVP increased significantly after AHH in groupⅡ(P0.01).MAP in group Ⅲ was significantly lower than in groupⅠand groupⅡ(P0.01).Blood loss and blood transfusion were significantly lower in group Ⅲ than in groupⅠand groupⅡ(P0.01).Conclusion AHH combined with controlled hypotension induced by urapidil can make hymodynamic stable,decrease blood loss,reduce transfusion of homologous blood,and has no adverse effects on tissue perfusion." @default.
- W2359717565 created "2016-06-24" @default.
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- W2359717565 date "2008-01-01" @default.
- W2359717565 modified "2023-09-23" @default.
- W2359717565 title "Clinical application of acute hypervolemic hemodilution combined with controlled hypotension induced by urapidil" @default.
- W2359717565 hasPublicationYear "2008" @default.
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