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- W2359761955 abstract "Objective To observe the effects of shuxuening parenteral solution on the activities of SDH and CK-BB in brain tissue after local cerebral ischemia/reperfusion in MACO rats. Methods The local ischemia/ reperfusion model was establish-ed by intraluminal thread occlusion of the middle cerebral artery ( MCAO) ,the animals were randomly divided into sham group,model group,shuxuening parenteral solution and chuan-xiongqin group. The mitochondria was obtained by density-cenirifu-gation and speed-centrifu-gation,then activities of SDH were tested. Activities of CK-BB were measured by using biochemieal methods. Results The activity of SDH in model group was lower than that in sham group in MCAO rats,but the activity of CK-BBT was higher( P 0. 05 or P 0. 01). the activities of SDH in two treatment groups for 3d and 7d were higher than those in model group,the activity of CK-BB was lower in twol treatment groups ( P 0. 05) ; There was no significant differece shuxuening parenteral solution group to chuan-xiongqin group is SDH and CK| BB activity. Conclusion Shuxuening parenteral solution could protect from pathologic injury after focal cerebral ischemia and reperfusion in MCAO rats by promoting ctivities of SDH and inhibiting ctivities of CK-BB." @default.
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- W2359761955 date "2010-01-01" @default.
- W2359761955 modified "2023-09-25" @default.
- W2359761955 title "Effect of extract of ginkgo biloba leaves injection on the activities of SDH and CK-BB in brain tissue after local cerebral ischemia/reperfusion in MACO rats." @default.
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