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- W2359792485 abstract "Objective To explore the influence of puerarin on the formation and development of periodontal inflam-mation in ovariectomized rats.Methods The female SD rats of 3 months old are randomly divided into the following 6 groups with 10 rats each:(A) control;(B) periodontal ligation;(C) ovariectomy;(D) ovariectomy and periodontal ligation;(E) ovariectomy and puerarin;(F) ovariectomy and periodontal ligation and puerarin.The rats in group D,E,F are extirpated of their ovaries on both sides through the incision in their abdomen respectively.The rats in group B and C were extirpated of a small amount of fat tissue but keep their ovaries.As for the rats in every periodontal ligated operation,their first molar on the right were ligated at the top with 0.2 mm steel wires.The rats in group E and F were injected 100 mg/kg puerarin after their operation,while the rats in group B and D injected with physiological saline every day.After 4,8 and 12 weeks of the operation,to observe the alveolar bone absorption and pathological change of tissue.Results The amount of the alveolar bone absorption of group with puerarin is less than that without puerarin.Osteoporosis in group with puerarin is less than that in group without puerarin.Conclusion Puerarin owns weak protective function for periodontal inflammation caused by the lost of estrogen." @default.
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- W2359792485 date "2010-01-01" @default.
- W2359792485 modified "2023-09-24" @default.
- W2359792485 title "Experimental Study of the Influence of Puerarin on Periodontal Inflammation in Ovariectomized Rats" @default.
- W2359792485 hasPublicationYear "2010" @default.
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