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- W2359831946 abstract "AIM: To analyze the characteristics of immune response in the animals after transplantation of bone marrow stromal cells(BMSCs) or non-BMSCs-derived cells.METHODS: Rat BMSCs and Buffalo rat liver(BRL) cells were transplanted into SD rats and New Zealand rabbits by intravenous and subcutaneous injections.The differences of immune response in the animals received these two types of cells were evaluated by comparative analysis of the lymphocytes and monocytes in peripheral blood as well as the histopathological characteristics of the subcutaneous transplantation sites.RESULTS: The increase intensity of the lymphocyte number in BMSCs group was lower than that in BRL group,regardless of allograft or xenograft.The immune reaction of the animals to BMSCs transplantation was a little slower.It was obviously dissimilar that the increase intensity of monocyte number in BMSCs group was higher than that in BRL group.Pathological cutaneous sections showed that neither obvious necrosis nor inflammatory cells was observed in the vicinity of BMSCs transplantation sites.CONCLUSION: The intensity of immune response induced by BMSCs is lower than that by BRL cells.The anti-rejection ability of BMSCs in cell transplantation is better than that of BRL cells." @default.
- W2359831946 created "2016-06-24" @default.
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- W2359831946 date "2011-01-01" @default.
- W2359831946 modified "2023-09-28" @default.
- W2359831946 title "Difference of immune response to transplantation of BMSCs and non-BMSCs-derived cells in animals" @default.
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