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- W2359834357 abstract "Objective To analyze the clinical characteristics and curative effect of terminal retinoblastoma(Rb).Methods The clinical document of 133 cases(162 eyes,78 male,55 female) with extraocular and metastasis stage of Rb confirmed in Department of Pediatrics of Tongren Hospital from Sep.2005 to May 2010 were retrospectively analyzed.The average age of 133 cases was 2.04 years old(range 0.33-12.66 years old);primary eye types:the right eyes diagnosed primarily were 48 cases(extraocular 36 cases,metastasis stage 12 cases),left eyes diagnosed primarily were 56 cases(extraocular 46 cases,metastasis stage 10 cases),and double eyes diagnosed primarily were 29 cases.Results Leucocoria was the most common manifestation of terminal Rb with the primary diagnosis rate was 69.92%(93/133 cases) based on this symptom;secondly,lacrimation,flare,photophobia,exophthalmos(10.52%) and side-glance(9.77%),weak-eyed,blindness,cataract(6.77%),misdiagnose(1.51%),recur after operation(1.51%).The hospitalized rate of male [58%(78/133 cases)]was more than that of female.Seven cases(5.26%) showed the positive family history in all of cases.In all the 133 cases,131 cases(98.49%) had an increase in neurone specific enolase(NSE),the max was 370.00 μg·L-1.The total survival rate was 82.35%(98/119 cases),14 cases(in the metastasis stage 9 cases,extraocular 5 cases) given up treatment and lost followed-up.One hundred and nineteen cases were followed up:the median follow-up visit was 27 months,the survival rate was 82.35%(98/119 cases).Moreover,the survival rate of Rb in the metastasis stage was 26.08%(6/23 cases);the survival rate of Rb in the extraocluar stage was 95.83%(92/96 cases).Conclusions The mortality of terminal Rb is very high,especially in metastasis stage.Therefore,it is very important to diagnose early and give an overall treatment." @default.
- W2359834357 created "2016-06-24" @default.
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- W2359834357 date "2011-01-01" @default.
- W2359834357 modified "2023-09-23" @default.
- W2359834357 title "Clinical Analysis of 133 Cases of Extraocular Stage and Metastasis Stage Metastatic Retinoblastoma" @default.
- W2359834357 hasPublicationYear "2011" @default.
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