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- W2359844062 abstract "[Objective] To evaluate the expression of vascular endothelial growth factor (VEGF) in blood serum and its relation to metastasis and prognosis significance in breast cancer. [Methods] The level of VEGF in blood serum was detected in 31 cases of breast carcinomas pre-operation and 12 cases of breast carcinomas after-operation by the method of enzyme-linked immunosorbent assay(ELISA). [Results] The concentration of VEGF in blood serum difference among breast carcinoma, breast benign tumor and normal women was significant. The concentration of VEGF in blood serum of breast carcinoma was closely related to clinical stage, axillary lymph node metastasis, distant metastasis. There was no significant relationship between the concentration of VEGF in blood serum of breast carcinoma and histological type or tumor diameter. In follow-up study after operation, the concentration of VEGF in blood serum of breast carcinoma which had tumor metastasis and recurrence after operation was significantly higher than that of no tumor metastasis and recurrence. Before operation, the concentration of VEGF in blood serum of breast carcinoma was higher in the cases with tumor metastasis and recurrence after operation, than in those with no tumor metastasis and recurrence after operation. [Conclusions] The VEGF levels in blood serum of breast carcinoma can be conducted as an assisted marker to differential diagnosis of breast tumor binding screenage results, it also can be conducted as an independent marker to predict the clinical TNM stage, tumor metastasis and necessary chemotherapy. It is useful for judgeing breast carcinoma recurrence and treament effects to monitor the VEGF level in blood serum of breast carcinoma after operation periodicly." @default.
- W2359844062 created "2016-06-24" @default.
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- W2359844062 date "2006-01-01" @default.
- W2359844062 modified "2023-09-23" @default.
- W2359844062 title "Expression of vascular endothelial growth factor in blood serum of patients with human breast carcinoma and its clinical significance" @default.
- W2359844062 hasPublicationYear "2006" @default.
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