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- W2359883359 abstract "Cyclin is one of the most important regulatory factors to promote cell cycle progression,and also plays roles in individual development and formation of tumors.In order to explore the tissue expression of cyclin genes in silkworm (Bombyx mori) ,we designed primers according to information from silkworm genome database and cloned 5 cyclin genes.The result of sequence analysis showed that cyclinA,cyclinB and cyclinB3 has 7 exons respectively,cyclinE has 8 exons,and cyclinL1 has only 1 exon.cyclinA and cyclinE have multiple splicing patterns.cyclinA mainly has 2 141 bp and 2 173 bp transcripts with variation at the 7th exon.cyclinE has 1 422 bp,1 290 bp,1194 bp and other length transcripts with variations at the 5th to 7th exons.cyclinB,cyclinB3 and cyclinL1 genes are relatively stable.Tissue expression of the cloned silkworm cyclin family genes was varied.cyclinA gene was only expressed in testis.cyclinB3 gene was expressed apparently in testis and ovarian.cyclinE gene was expressed in all 8 tissues namely silk gland,brain,fat body,midgut,Malpighian tubule,testis,ovarian and hemolymph.cyclinB and cyclinL1 genes were expressed in other 7 tissues except silk gland or hemolymph.The above results provide good references for further study on functions of various cyclins in insect molting,metamorphosis and other physiological processes." @default.
- W2359883359 created "2016-06-24" @default.
- W2359883359 creator A5071915668 @default.
- W2359883359 date "2010-01-01" @default.
- W2359883359 modified "2023-09-22" @default.
- W2359883359 title "Cloning,Structural Characterization and Expression Analysis of Cyclin Family Genes in Silkworm,Bombyx mori" @default.
- W2359883359 hasPublicationYear "2010" @default.
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