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- W2359885809 abstract "Bronchoalveolar lavage (BAL) studies were carried out in 27 sputum smear negative butradiographic probable pulmonary tuberculosis patients to characterize the inflammatory and Immuneeffector cells in the lower respiratory tract and in 17 normal subjects. The diagnosis of active pulmonarytuberculosis was confirmed by isolation of Mycobacterium tuberculosis in culture from sputum and/orlavage specimens. BAL was done first from radiologically normal lobe and then from radiologicallyabnormal lobe prior to treatment and the BAL fluids were analyzed separately. Two groups were identifiedbased on lavage results. One group (macrophage predominant) had significantly elevated total cells andalveolar macrophages in both radiologically normal (p<0.01) and abnormal lobes (p<0.001) compared tonormal controls. The other group (lymphocyte predominant) had expanded numbers of total cells(p<0.01), lymphocytes (p<0.01), neutrophlls (p<0.05) and eosinophils (p<0.01) in radiologically abnormallobe. The cell profile in radiologically normal lobe in lymphocyte predominant group was within normallimits. These results suggest that two distinct cell profiles, in one group an increase in alveolarmacrophages and in the other an increase in lymphocytes can occur In the lower respiratory tract ofpatients with sputum smear negative, but radiographic probable pulmonary tuberculosis." @default.
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- W2359885809 date "1994-05-01" @default.
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- W2359885809 title "Characterization of lower respiratory tract inflammation in patients with smear negative pulmonary tuberculosis" @default.
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