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- W2359892008 abstract "ObjectiveTo study the mechanisms of Ca 2+ overload in neurons induced by oxygen free radicals. Methods L-type calcium channel currents were recorded from human neuroblastoma cells, SH-SY5Y , with whole-cell patch-clamp techniques. ResultsH 2O 2 was shown to increases L-type calcium channel currents (I Ca,L) concentration dependently, and to shift the I-V curves of I Ca,L downwardly. ConclusionH 2O 2 could activate significantly L-type calcium channel in SH-SY5Y human neuroblastoma cells, and it might be one of the mechanisms of Ca 2+ overload in neurons induced by oxygen free radicals. [" @default.
- W2359892008 created "2016-06-24" @default.
- W2359892008 creator A5029251187 @default.
- W2359892008 date "2004-01-01" @default.
- W2359892008 modified "2023-09-24" @default.
- W2359892008 title "EFFECTS OF H_2O_2 ON L-TYPE CALCIUM CURRENT IN SH-SY5Y HUMAN NEUROBLASTOMA CELLS" @default.
- W2359892008 hasPublicationYear "2004" @default.
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