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- W2359953315 abstract "Objective:To investigate the relationships between multidrug resistance gene product P-gp expression and the clinical pathological characteristics in human colorectal carcinoma.Methods:P-gp expression in 80 cases of colorectal carcinoma tissue were determined by SP immunohistochemical staining.Results:The positive rate of P-gp expression in colorectal carcinoma was 43.75%(35/80).The P-gp expression had no relations with differentiation degree,clinical stage,inf iltration depth and lymph node metastasis(P 0.05);But had relations with age,the positive rate of P-gp expression in colorectal carcinoma of patients≥ 60-year old was obviously lower than patients under 60(P 0.01).Conclusions:The P-gp expression in colorectal carcinoma is fairly high and has relations with age.It is very important to detect P-gp expression when determine individualization treatment." @default.
- W2359953315 created "2016-06-24" @default.
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- W2359953315 date "2010-01-01" @default.
- W2359953315 modified "2023-09-26" @default.
- W2359953315 title "EXPRESSION AND CLINICAL SIGNIFICANCE OF P-GP IN COLORECTAL CARCINOMA" @default.
- W2359953315 hasPublicationYear "2010" @default.
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