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- W2359968266 abstract "Aim: To analysis the antibiotic resistance of Pseudomonas aeruginosa in our hospitalduring 2007-2009,so as to guide the using of antibiotics in hospital reasonably,and the role of OprD in imipenem-resistant Pseudomonas aeruginosa was also investigated.Methods: The the coding gene of OprD was detected with PCR.Whonet 5.4 software was used to analyze the results of drug sensitivity tests.Results: 132(13.6%),159(14.1%) and 173(19.3%) Pseudomonas aeruginosa strains were isolated in 2007,2008 and 2009 respectively.Most of the strains were obtained from Department of Respiratory Medicine and ICU,and sputum was the main sample.Of the 474 Pseudomonas aeruginosa,resistantance rate to MH,MXF,IPM,and MEM were 89.50%,81.50%,37.1%,and 34.80%,respectively.49.50% Pseudomonas aeruginosa were multidrug resistant strains,and 7.80% strains were resistant to all the antibiotics.One of the eight random selected imipenem-resistant Pseudomonas aeruginosa did not detect OprD coding gene.Conclusion:The total antibiotic resistance of Pseudomonas aeruginosa was critical and the resistantance rate to imipenem was also high.Deletion of OprD was one of the imipenem-resistant mechanisms in Pseudomonas aeruginosa." @default.
- W2359968266 created "2016-06-24" @default.
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- W2359968266 date "2011-01-01" @default.
- W2359968266 modified "2023-09-22" @default.
- W2359968266 title "Antibiotic resistance analysis and investigation of oprD in imipenem-resistant pseudomonas aeruginosa" @default.
- W2359968266 hasPublicationYear "2011" @default.
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