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- W2359976694 abstract "OBJECTIVE:To establish HPLC method for the determination of the contents of tretinoin and halcinonide in psoriasis cream.METHODS:The determination was performed on Hypersil C18 column with column temperature at 40℃.The mobile phase consisted of methanol-0.5% aqueous acetic acid at a flow rate of 1.2mL· min-1 by gradient elution.The UV detection wavelength was set at 267nm and the sample size was 20μ L.RESULTS:The linear ranges of tretinoin and halcinonide were 4～ 30,and 4～ 50μ g· mL-1(r=0.999 9),respectively,with average recovery rates at 99.09% and 98.91% and RSD at 0.37% and 0.20%,respectively.CONCLUSION:The established method is simple and accurate,and suitable for the quality control of psoriasis cream." @default.
- W2359976694 created "2016-06-24" @default.
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- W2359976694 date "2007-01-01" @default.
- W2359976694 modified "2023-09-25" @default.
- W2359976694 title "Determination of Tretinoin and Halcinonide in Psoriasis Cream by HPLC" @default.
- W2359976694 hasPublicationYear "2007" @default.
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