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- W2359983762 abstract "Objective: Our aims were to study the expressions of substance P(SP) in trigeminal ganglia(TG) in rats after occlusal reconstruction, and to discuss the mechanism of temporomandibular disorders. Methods: 30 Wistar male rats were randomly divided into 3 experimental groups and 3 control groups, 5 rats in each group. The molar of right maxillary and mandibular of rats in experimental groups were ground to the gingival level without occlusal contact. The occlusal contact was recovered by stoping grounding molar of the rats. The section of trigeminal ganglia was underwent the immunohistological study to evaluate the expressions of SP by using SABC method. Light microscope and microscopic photo analytic software and SPSS10.0 statistical software were used. Results: The percentage of SP positive neurons in TG with unilateral chewing significantly decreased compared with control group (P0.01). The decreased extent in non-chewing side was much lower than that in the chewing side (P0.05), There was no significant difference in the percentage of SP positive neurons between early occlusal reconstruction experiment group and control group (P0.05), and there was no significantly difference between non-chewing side and chewing side (P0.05). There was significant difference in the percentage of SP positive neurons between later occlusal reconstruction experiment group and control group (P0.01), and there was significant difference between non-chewing side and chewing side (P0.05). Conclusion: The expressions of SP in TG can recover to normal after early occlusal reconstruction but not later occlusal reconstruction.SP might participate in the histopathologic mechanism of temporomandibular disorders." @default.
- W2359983762 created "2016-06-24" @default.
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- W2359983762 date "2007-01-01" @default.
- W2359983762 modified "2023-09-28" @default.
- W2359983762 title "Expressions of Substance P in Trigeminal Ganglia in Rats after Occlusal Reconstruction" @default.
- W2359983762 hasPublicationYear "2007" @default.
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