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- W2360005140 abstract "Poly(dl -lactide- co -glycolide)75/25(PLGA75/25) porous scaffolds for tissue engineering were fabricated by a novel technique of the low heat-high pressure without using organic solvents. The porosity of the scaffolds was up to 90%. Scanning electron micrograph (SEM) observations revealed that the pore size and distribution were uniform. The surface of the scaffolds treated with alcohol appeared lots of micro-caves. The morphology of the scaffolds were improved after modification by alginate calcium. The compression strength and the hydrophilicity of the scaffolds were improved after modification by the above two methods. Though the scaffolds with higher porosity degraded a little slower, the degradation behaviors in vitro of the two scaffolds with porosity of 90% and 92% respectively were mainly consistent: the intrinsic viscosity of the scaffold material and the compression strength of scaffolds decreased very fast, but the mass lost more slowly and was about 3 % mass loss after degrading for 6 weeks. The porous structure and morphology of the scaffolds held well after degrading for 3 weeks, which is expected to play an important support role in cell transplant and tissue regeneration." @default.
- W2360005140 created "2016-06-24" @default.
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- W2360005140 date "2003-01-01" @default.
- W2360005140 modified "2023-09-28" @default.
- W2360005140 title "Scaffolds with High Porosity for Tissue Engineering Fabricated by Low Heat-High Pressure and their Degradation in Vitro" @default.
- W2360005140 hasPublicationYear "2003" @default.
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