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- W2360036715 abstract "ObjectiveTo detect messenger RNA (mRNA) expression of MMP-9 and VEGF in pituitary tumors. And explore the relationship among MM-9, VEGF mRNA and invasiveness of pituitary adenomas, and investigate its clinical value. MethodsMMP-9 and VEGF mRNA expression was determined in 20 invasive pituitary adenomas and 10 non-invasive pituitary adenomas by using comparative reverse transcription-polymerase chain reaction (RT-PCR). The correlation between mRNA expression of MM-9 and VEGF and the correlation between mRNA expression of MM-9, VEGF and tumor invasiveness were studied. ResultBoth mRNA expression of MMP-9 and VEGF increased in invasive pituitary adenomas (P 0.01 ). There were positively correlations between MMP-2 and TIMP-2. ConclusionThe expression of MMP-9, VEGF mRNA were significant correlation in invasive pituitary adenomas, and they play a cooperated role in the invasiveness and angiogenesis of invasive pituitary tumors." @default.
- W2360036715 created "2016-06-24" @default.
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- W2360036715 date "2003-01-01" @default.
- W2360036715 modified "2023-09-24" @default.
- W2360036715 title "The Study of Expression and Relation BetweenVascular Endothelial Growth Factor (VEGF)and MMP-9 in Pituitary Adenomas" @default.
- W2360036715 hasPublicationYear "2003" @default.
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