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- W2360051093 abstract "HNF1α is one of the liver-enriched transcription factors,and is involved in many tissue-specific expressions of hepatic genes and maintenance of the hepatic phenotypes and functions.HNF1α,as a complex,by interacting with a variety of proteins,regulates the transcription.Multiple co-activators of HNF1α are required for the functions of HNF1α complex.The dynamic changes of members of the HNF1α complex play critical roles in tissue-specific expression,homeostasis,injury repairing,and drug metabolism.Mutants in HNF1α can change the interaction between HNF1α and its partners,alter the expressions of genes and lead to maturity-onset diabetes of the young type 3(MODY3)." @default.
- W2360051093 created "2016-06-24" @default.
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- W2360051093 date "2007-01-01" @default.
- W2360051093 modified "2023-09-23" @default.
- W2360051093 title "Advances in the Research of HNF1α Complex" @default.
- W2360051093 hasPublicationYear "2007" @default.
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