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- W2360075158 abstract "Objective To observe the effect of sheep bone collagen peptide (SBCP) on blood pressure and blood fat in experimental hypertensive rats. Method Healthy SD rats were administered by oral with No synthase inhibitor L-NAME to build hypertension model of nitric oxide deficiency. Forty SD rats were divided randomly into 4 groups:blank (distilled water), control (L-NAME,15 mg/kg bw·d), sample 1 (L-NAME, 15 mg/kg bw·d and SBCP 1, 1000 mg/kg bw·d) and sample 2 (L-NAME, 15 mg/kg bw·d and SBCP 2, 1000 mg/kg bw·d). We observed the living situation and measured the blood pressure, heart rate and blood lipid at regular intervals. Results Compared with the blank group, the sample 1, 2 and the control group had higher blood pressure after giving L-NAME one week. Then, the blood pressure of sample 1 and sample 2 group began to decline persistently, and was significantly lower than the control from the third week to the end of this experiment. SBCP had no significant effect on heart rate, body weight gain, feed intake and feed efficiency. All rats have normal blood lipid from the beginning to end. Conclucion SBCP 1000 mg/ ( kg bw·d ) could effectively control the blood pressure, while it has no effect on heart rate and blood lipid." @default.
- W2360075158 created "2016-06-24" @default.
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- W2360075158 date "2008-01-01" @default.
- W2360075158 modified "2023-09-26" @default.
- W2360075158 title "EFFECTS OF SHEEP BONE COLLAGEN PEPTIDE ON BLOOD PRESSURE AND BLOOD LIPID IN EXPERIMENTAL HYPERTENSIVE RATS" @default.
- W2360075158 hasPublicationYear "2008" @default.
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