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- W2360077884 abstract "Objective To explore the efficacy and tolerability of aripiprazole in the adjunctive treatment for risperidone in hyperprolactinemia.Methods A total of 88 schizophrenia patients randomly divided into Risperidone associated with aripiprazole treatment group(n=44) and single Risperidone group(n=44), for 4 weeks.Serum prolactin levels were measur weeks 0, 2, 4. Symptoms and side effects were assessed with Positive and Negative Syndrome Scale( PANSS), Extrapyra Symptom Rating Scale(ESRS),Treatment Emergent Symptom Scale(TESS) at weeks 0, 2, 4.ResultsSerum prolactin were reduced significantly at the second week, and the fourth week in single Risperidone group; however this difference in Risperidone associated with aripiprazole group dosed at 5 mg/ day was not statistically significant before and after the study. Other side effects were less and the total prevalence of side effects was similar in two groups.Conclusion Efficacy and tolerability of aripiprazole in the adjunctive treatment for risperidone induced hyperprolactinemia is very good." @default.
- W2360077884 created "2016-06-24" @default.
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- W2360077884 date "2013-01-01" @default.
- W2360077884 modified "2023-09-23" @default.
- W2360077884 title "Controlled clinical study of adjunctive treatment with aripiprazole for risperidone induced hyperprolactinemia" @default.
- W2360077884 hasPublicationYear "2013" @default.
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