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- W2360084698 abstract "Objective To study the inhibitory effect of Erigeron canadensis L.on the growth and invasiveness of human prostate cancer cell(PC-3M) in vitro.Methods The effect s of Erigeron canadensis L.on the growth of PC-3M cells were detected by CCK-8 kit.The PC-3Mcells treated by 5-FU were used as positive cont rol group and thePC-3Mcells without any treatment as negative control group,the PC-3Mcells treated by Erigeron canadensis L.were used as experimental groups.Meanwhile the grrwth of PC-3M cells after treated by Erigeron canadensis L.was assessed by cell growth curve.And the morphological changes of PC-3M cells under different concent rations of medicine were observed.Immunocytochemical staining was used to evaluate MMP-9 expression level.Results Eigeron Canadensis L.inhibitedthe growth of PC-3M cells and the value of IC50 was 0.097 mg·L-1.After treatment,the growth of PC-3M cells slowed,and the cells became longth,adherence decreased.Drugs after the expression of MMP9 was significantly weaker than the control group(P0.001).Conclusion Erigeron canadensis L.inhibit cell growth,invasion of PC3M." @default.
- W2360084698 created "2016-06-24" @default.
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- W2360084698 date "2011-01-01" @default.
- W2360084698 modified "2023-09-25" @default.
- W2360084698 title "The effect of Erigeron canadensis L.on prostate cancer cell" @default.
- W2360084698 hasPublicationYear "2011" @default.
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