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- W2360087272 abstract "Objective To observe the protective effect of Astragalus injection on human umbilical vein endothelial cells(HUVEC) injured by nicotine and explore its molecular mechanism.Methods The effects of nicotine,Astragalus on the growth of HUVEC were detected respectively by MTT method,the levels of total NO,total NOS and ET-1 were detected by nitrate reductase assay,chemical colorimetry and enzyme linked immunosorbent assay respectively.Results The levels of total NO and total NOS were decreased significantly,and ET-1 level was increased significantly after nicotine intervention(P0.01).The levels of total NO and total NOS were increased significantly,and ET-1 level was decreased significantly after Astragalus intervention(P0.01).The levels of total NO and total NOS of HUVEC received Astragalus pretreatment and nicotine intervention were higher significantly than that received nicotine intervention only(P0.05),and ET-1 level was lower significantly than that received nicotine intervention only(P0.05).Conclusion Astragalus can protect HUVEC against nicotine to some extent." @default.
- W2360087272 created "2016-06-24" @default.
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- W2360087272 date "2011-01-01" @default.
- W2360087272 modified "2023-09-26" @default.
- W2360087272 title "Protective Effects of Astragalus Injection on Human Umbilical Vein Endothelial Cells Injured by Nicotine" @default.
- W2360087272 hasPublicationYear "2011" @default.
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